Harnessing Gamma Delta TCR Signaling & Alpha Beta T Cell Biology to Balance Cytotoxicity, Target Recognition & Exhaustion

Time: 1:30 pm
day: Day 2 pm track b


  • Contrasting the clinical profile of gamma delta T vs. alpha beta T cells in the clinic
  • Outlining the clinical mechanism of action of gamma delta TCR signaling and activation, and the impact on cell exhaustion and persistence
  • Understanding the importance of TCR specificity and the balance of direction vs. exhaustion
  • Gauging the signal strength required to elicit a potent and durable response